Obstetrics & Gynecology Journals-Lupine Publishers



Uterine Leiomyoma (UL) is the most prevalent benigngynecological tumor in the female population. The tumor originates from the smooth muscle of the myometrium [1-3]. As many as 1 in 5 women in child-bearing age may have UL, and between 20 to 80% of all women may have the tumor by the age of 50 [4]. It seems that UL is more common in black than white Caucasian women [5,6]. The exact a etiology of UL is unknown, but there is considerable evidence that it might be due to a combination of factors, such as: hormonal, environmental, chromosomal, genetic drivers, cellular modulation, and phenotypical changes [7-9,2,10,11]. The UL have different sizes, locations and growth pattern and it may attain enough volume to significantly distort the uterine cavity and endometrial surface and affect the menstrual flow [12,13]. It may also affect reproductive outcomes and may be associated with pregnancy loss, preterm birth, dystocia and fetal malpresentation.



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